Akira

  I'm not gonna say much about this one because if you haven't seen it you really don't know want your missing.  The best advice I can give is just make sure you get the subtitled version not the dubbed, because the dubbed has the same women doing all the voices, which is extremely gay.  If you didn't already know this is the only anime suggested by Siskel & Ebert.  Final statement is best summed up by say either you love or you hate it there is no gray area.